Leigh disease

Term ID

DOID:3652

Synonyms

• Infantile necrotizing encephalomyelopathy
• juvenile subacute necrotizing encephalomyelopathy
• Leigh syndrome
• subacute necrotizing encephalomyelopathy

Definition

A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity. (4)

References

• GARD:6877
• ICD10CM:G31.82
• MESH:D007888
• NCI:C84814
• OMIM:256000
• ORDO:506
• SNOMEDCT_US_2023_03_01:29570005
• UMLS_CUI:C0023264

Ontology

Human Disease   ( DOID:3652 )