tetanus

Term ID

DOID:11338

Synonyms

• clostridial tetanus
• Infection due to Clostridium tetani

Definition

A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli. http://en.wikipedia.org/wiki/Tetanus

References

• GARD:5144
• ICD10CM:A35
• ICD9CM:037
• MESH:D013742
• NCI:C85185
• SNOMEDCT_US_2023_03_01:154312006
• UMLS_CUI:C0039614

Ontology

Human Disease   ( DOID:11338 )