T2-low asthma

Term ID

DOID:0080818

Synonyms

• type 2 low endotype

Definition

A chronic asthma that is characterized by the pathophysiology phenotype combination (endotype) of non-atopic, smoking, obesity related, and elderly and that is characterized by neutrophilic (sputum neutrophils > 40–60%) or paucigranulocytic (i.e., normal sputum levels of both eosinophils and neutrophils) inflammation and a lack of response to corticosteroid therapy. https://pubmed.ncbi.nlm.nih.gov/21281866/

References

Ontology

Human Disease   ( DOID:0080818 )