NUT midline carcinoma

Term ID

DOID:0060463

Synonyms

• nuclear protein in testis midline carcinoma

Definition

A carcinoma that is characterized by a BRD4-NUT translocation involving the rearrangement of the bromodomain-containing protein 4 (BRD4) and the gene encoding nuclear protein of the testis (NUT) at 15q14, BRD4-NUT t(15;19)(q14;q13.1) and arises from midline epithelial structures, most commonly the head, neck, and mediastinum. (7)

References

• NCI:C45716
• SNOMEDCT_US_2023_03_01:733922002
• UMLS_CUI:C1707291

Ontology

Human Disease   ( DOID:0060463 )