CD4-positive, CD8-intermediate double-positive thymocyte

Term ID

CL:0002431

Synonyms

T.4int8+.th

Definition

A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. http://www.immgen.org/index_content.html

References

Ontology

Cell Ontology

Relationships

develops from: CD69-positive double-positive thymocyte

CD69-positive double-positive thymocyte Show first 5 Terms
develops into: CD69-positive, CD4-positive single-positive thymocyte

CD69-positive, CD4-positive single-positive thymocyte Show first 5 Terms
is a type of: double-positive, alpha-beta thymocyte

double-positive, alpha-beta thymocyte Show first 5 Terms
has_high_plasma_membrane_amount: alpha-beta T cell receptor complex

alpha-beta T cell receptor complex Show first 5 Terms
has_low_plasma_membrane_amount: T cell receptor co-receptor CD8

T cell receptor co-receptor CD8 Show first 5 Terms
has_plasma_membrane_part: CD69 molecule

CD69 molecule Show first 5 Terms
participates_in: positive T cell selection

positive T cell selection Show first 5 Terms