common myeloid progenitor, CD34-positive

Term ID

CL:0001059

Synonyms

CFU-GEMM
CFU-S
CMP
colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte
common myeloid precursor, CD34-positive
multipotential myeloid stem cell
myeloid stem cell
pluripotent stem cell (bone marrow)

Definition

A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. (4)

References

Ontology

Cell Ontology

Relationships

is a type of: common myeloid progenitor precursor cell

common myeloid progenitor precursor cell Show first 5 Terms
has subtype: CD34-positive, CD38-positive common myeloid progenitor Kit-positive, CD34-positive common myeloid progenitor

CD34-positive, CD38-positive common myeloid progenitor Kit-positive, CD34-positive common myeloid progenitor Show first 5 Terms
capable_of: myeloid dendritic cell differentiation myeloid leukocyte differentiation

myeloid dendritic cell differentiation myeloid leukocyte differentiation Show first 5 Terms
has_part: CCAAT/enhancer-binding protein alpha endothelial transcription factor GATA-2 erythroid transcription factor transcription factor PU.1

CCAAT/enhancer-binding protein alpha endothelial transcription factor GATA-2 erythroid transcription factor transcription factor PU.1 Show first 5 Terms
has_plasma_membrane_part: CD34 molecule

CD34 molecule Show first 5 Terms