naive T cell

Term ID

CL:0000898

Synonyms

naive T lymphocyte
naive T-cell
naive T-lymphocyte

Definition

Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. 19100699

References

Ontology

Cell Ontology

Relationships

is a type of: mature T cell

mature T cell Show first 5 Terms
has subtype: naive regulatory T cell naive thymus-derived CD4-positive, alpha-beta T cell naive thymus-derived CD8-positive, alpha-beta T cell

naive regulatory T cell naive thymus-derived CD4-positive, alpha-beta T cell naive thymus-derived CD8-positive, alpha-beta T cell Show first 5 Terms
has_completed: T cell selection

T cell selection Show first 5 Terms
has_high_plasma_membrane_amount: L-selectin

L-selectin Show first 5 Terms
has_low_plasma_membrane_amount: CD44 molecule

CD44 molecule Show first 5 Terms
has_plasma_membrane_part: C-C chemokine receptor type 7 interleukin-7 receptor subunit alpha receptor-type tyrosine-protein phosphatase C isoform CD45RA

C-C chemokine receptor type 7 interleukin-7 receptor subunit alpha receptor-type tyrosine-protein phosphatase C isoform CD45RA Show first 5 Terms
inverse disjoint_from: memory T cell

memory T cell Show first 5 Terms