mast cell progenitor

Term ID

CL:0000831

Synonyms

CFU-Mast
CFU-MC
colony forming unit mast cell
MCP

Definition

A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. (3)

References

Ontology

Cell Ontology

Relationships

develops from: basophil mast progenitor cell

basophil mast progenitor cell Show first 5 Terms
develops into: mast cell

mast cell Show first 5 Terms
is a type of: myeloid cell myeloid lineage restricted progenitor cell

myeloid cell myeloid lineage restricted progenitor cell Show first 5 Terms
has subtype: Fc-epsilon RIalpha-low mast cell progenitor

Fc-epsilon RIalpha-low mast cell progenitor Show first 5 Terms
capable_of: mast cell differentiation

mast cell differentiation Show first 5 Terms
has_high_plasma_membrane_amount: integrin beta-7

integrin beta-7 Show first 5 Terms
has_low_plasma_membrane_amount: high affinity immunoglobulin epsilon receptor subunit alpha mast/stem cell growth factor receptor

high affinity immunoglobulin epsilon receptor subunit alpha mast/stem cell growth factor receptor Show first 5 Terms
has_part: endothelial transcription factor GATA-2 erythroid transcription factor

endothelial transcription factor GATA-2 erythroid transcription factor Show first 5 Terms
has_plasma_membrane_part: CD9 molecule transmembrane emp24 domain-containing protein 1

CD9 molecule transmembrane emp24 domain-containing protein 1 Show first 5 Terms
lacks_part: CCAAT/enhancer-binding protein alpha

CCAAT/enhancer-binding protein alpha Show first 5 Terms
lacks_plasma_membrane_part: CD2 molecule CD3 epsilon CD4 molecule CD14 molecule CD19 molecule ... Show All 15 Terms

CD2 molecule CD3 epsilon CD4 molecule CD14 molecule CD19 molecule CD27 molecule integrin alpha-M lymphocyte antigen 6A-2/6E-1 lymphocyte antigen 6C2 lymphocyte antigen 6G lymphocyte antigen 76 membrane-spanning 4-domains subfamily A member 1 neural cell adhesion molecule 1 T-cell surface glycoprotein CD5 T-cell surface glycoprotein CD8 alpha chain Show first 5 Terms