pro-B cell

Term ID

CL:0000826

Synonyms

pre-B cell (Philadelphia nomenclature)
pre-pro B cell
pro-B lymphocyte
pro-B-cell
pro-B-lymphocyte
progenitor B cell
progenitor B lymphocyte
progenitor B-cell
progenitor B-lymphocyte

Definition

A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. (4)

References

BTO:0003104

Ontology

Cell Ontology

Relationships

develops from: common lymphoid progenitor

common lymphoid progenitor Show first 5 Terms
develops into: B cell lymphocyte of B lineage pre-B-I cell pre-B-II cell

B cell lymphocyte of B lineage pre-B-I cell pre-B-II cell Show first 5 Terms
is a type of: lymphoid lineage restricted progenitor cell

lymphoid lineage restricted progenitor cell Show first 5 Terms
has subtype: early pro-B cell Fraction A pre-pro B cell

early pro-B cell Fraction A pre-pro B cell Show first 5 Terms
has_part: DNA nucleotidylexotransferase paired box protein PAX-5

DNA nucleotidylexotransferase paired box protein PAX-5 Show first 5 Terms
inverse disjoint_from: precursor B cell

precursor B cell Show first 5 Terms
participates_in: immunoglobulin V(D)J recombination

immunoglobulin V(D)J recombination Show first 5 Terms