pro-NK cell

Term ID

CL:0000825

Synonyms

• natural killer cell progenitor
• NKP
• null cell
• preNK cell
• pro-natural killer cell

Definition

A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. (4)

References

Ontology

Cell Ontology