mesenchymal stem cell

Term ID

CL:0000134

Synonyms

• BMSC
• bone marrow stromal cells
• CFU-F
• colony-forming unit-fibroblast
• marrow stromal cells
• mesenchymal precursor cell
• mesenchymal progenitor cells
• mesenchymal stem cell
• mesenchymal stromal cell
• mesenchymal stromal cells
• MSC
• stem cells, mesenchymal

Definition

A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. (6)

References

• BTO:0002625
• BTO:0003298
• FMA:70546

Ontology

Cell Ontology