pristinamycin IIA

Term ID

CHEBI:9997

Synonyms

(3R,4R,5E,10E,12E,14S)-14-hydroxy-3-isopropyl-4,12-dimethyl-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
Mikamycin A
Ostreogrycin a
Streptogramin A
Virginiamycin factor M1
Virginiamycin M1

Definition

A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus.

References

CAS:21411-53-0
DrugBank:DB01669
KEGG:C11299
PDBeChem:VIR
PMID:15480455
PMID:24324222
PMID:24687494
PMID:25223995
PMID:3096930
PMID:5905315
Reaxys:71867
Wikipedia:Pristinamycin_IIA

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 1,3-oxazoles cyclic ketone enamide lactam macrolide ... Show All 10 Terms

1,3-oxazoles cyclic ketone enamide lactam macrolide macrolide antibiotic pyrroline secondary alcohol secondary carboxamide tertiary carboxamide Show first 5 Terms
has_role: antibacterial drug Mycoplasma genitalium metabolite

antibacterial drug Mycoplasma genitalium metabolite Show first 5 Terms
inverse has_functional_parent: dalfopristin

dalfopristin Show first 5 Terms
inverse has_part: virginiamycin

virginiamycin Show first 5 Terms

Phenotype

Phenotype resulting from pristinamycin IIA

Phenotype where environments contain pristinamycin IIA

Phenotype modified by environments containing pristinamycin IIA

Human Disease / Model Data

Citations