tienilic acid

Term ID

CHEBI:9590

Synonyms

• (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid
• (2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid
• 4-(2-Theonyl)-2,3-dichlorphenoxyessigsaeure
• 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid
• [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid
• acide tienilique
• acido tienilico
• acidum tienilicum
• Thienylic acid
• Ticrynafen
• tienilic acid

Definition

An aromatic ketone that is 2,3-dichlorophenoxyacetic acid in which the hydrogen at position 4 on the benzene ring is replaced by a thiophenecarbonyl group. A loop diuretic used to treat hypertension, it was withdrawn from the market in 1982 due to links with hepatitis.

References

• CAS:40180-04-9
• DrugBank:DB04831
• Drug_Central:2658
• KEGG:C11702
• KEGG:D02386
• LINCS:LSM-5478
• PMID:22462724
• PMID:23013248
• PMID:24575896
• PMID:2714684
• PMID:41229
• PMID:471149
• PMID:471154
• PMID:504040
• PMID:6996137
• PMID:7004678
• PMID:7074982
• PMID:7128663
• PMID:7398677
• PMID:8823314
• PMID:913063
• Reaxys:1260086
• Wikipedia:Tienilic_acid

Ontology

ChEBI  ( EBI )

Resources

CTD