tipiracil hydrochloride

Term ID

CHEBI:90877

Synonyms

• 1-[(5-chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]pyrrolidin-2-iminium chloride
• 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride
• tipiracil monohydrochloride
• tipiracil.HCl

Definition

A hydrochloride obtained by combining tipiracil with one equivalent of hydrochloric acid. Used in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.

References

• cas:183204-72-0
• kegg.drug:D10467
• pubmed:24562648
• pubmed:25230742
• pubmed:25750295
• pubmed:25812794
• pubmed:25900515
• pubmed:25901475
• pubmed:25970050
• pubmed:26084259
• pubmed:26163340
• pubmed:26197742
• pubmed:26254349
• pubmed:26370544
• pubmed:26428513
• pubmed:26509228
• pubmed:26557901
• pubmed:26677869
• pubmed:26722024
• pubmed:26723516
• reaxys:9299131
• wikipedia.en:Tipiracil

Ontology

ChEBI  ( EBI )