O-(chloroacetylcarbamoyl)fumagillol

Term ID

CHEBI:90748

Synonyms

(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl (chloroacetyl)carbamate
(CHLOROACETYL)CARBAMIC ACID (3R,4S,5S,5R)-5-METHOXY-4-[(2R,3R)-2-METHYL-3-(3-METHYL-2-BUTENYL)OXIRANYL]-1-OXASPIRO[2.5]OCT-6-YL ESTER
Agm 1470
AGM-1470
DRG-0148
O-chloroacetylcarbamoylfumagillol
TNP 470
TNP-470

Definition

A carbamate ester that is fumagillol in which the hydroxy group has been converted to the corresponding N-(chloroacetyl)carbamate derivative.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: carbamate ester organochlorine compound semisynthetic derivative sesquiterpenoid spiro-epoxide

carbamate ester organochlorine compound semisynthetic derivative sesquiterpenoid spiro-epoxide Show first 5 Terms
has_functional_parent: fumagillol

fumagillol Show first 5 Terms
has_role: angiogenesis inhibitor antineoplastic agent EC 1.5.1.3 (dihydrofolate reductase) inhibitor methionine aminopeptidase 2 inhibitor retinoic acid receptor alpha antagonist

angiogenesis inhibitor antineoplastic agent EC 1.5.1.3 (dihydrofolate reductase) inhibitor methionine aminopeptidase 2 inhibitor retinoic acid receptor alpha antagonist Show first 5 Terms

Phenotype

Phenotype resulting from O-(chloroacetylcarbamoyl)fumagillol

Phenotype where environments contain O-(chloroacetylcarbamoyl)fumagillol

Phenotype modified by environments containing O-(chloroacetylcarbamoyl)fumagillol

Human Disease / Model Data

Citations