Search Ontology:
ChEBI

pamapimod

Term ID
CHEBI:90685
Synonyms
  • 6-(2,4-difluorophenoxy)-2-[(1,5-dihydroxypentan-3-yl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
  • pamapimod
  • R1503
  • Ro 4402257
Definition
A member of the class of pyridopyrimidines that is 8-methylpyrido[2,3-d]pyrimidin-7(8H)-one carrying additional (1,5-dihydroxypentan-3-yl)amino and 2,4-difluorophenoxy substituents at positions 2 and 6 respectively. It is a potent inhibitor of MAPK and is used for treatment of rheumatoid arthritis.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from pamapimod
Phenotype where environments contain pamapimod
Phenotype modified by environments containing pamapimod
Human Disease / Model Data
Citations
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