PF-670462

Term ID

CHEBI:87236

Synonyms

4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyrimidin-2-amine dihydrochloride

Definition

A hydrochloride salt resulting from the formal reaction of 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine with 2 mol eq. of hydrogen chloride. It is a selective inhibitor of the delta- and epsilon-isoforms of casein kinase 1 (CK1delta and CK1epsilon).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride

hydrochloride Show first 5 Terms
has_part: PF-670462 free base(2+)

PF-670462 free base(2+) Show first 5 Terms
has_role: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor

EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from PF-670462

Phenotype where environments contain PF-670462

Phenotype modified by environments containing PF-670462

Human Disease / Model Data

Citations