Search Ontology:
ChEBI

potassium clavulanate

Term ID
CHEBI:85264
Synonyms
  • Clavulanate potassium
  • CVA
  • potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
Definition
A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
inverse has_part
Phenotype
Phenotype resulting from potassium clavulanate
Phenotype where environments contain potassium clavulanate
Phenotype modified by environments containing potassium clavulanate
Human Disease / Model Data
Citations