nintedanib esylate

Term ID

CHEBI:85170

Synonyms

methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate ethanesulfonate
Nintedanib ethanesulfonate
Ofev

Definition

An organosulfonate salt obtained by combining nintedanib with one molar equivalent of ethanesulfonic acid. A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer.

References

CAS:656247-18-6
KEGG:D10396
PMID:25430078
PMID:25628503
Reaxys:14300928

Ontology

ChEBI ( EBI )

Relationships

is a type of: organosulfonate salt

organosulfonate salt Show first 5 Terms
has_part: nintedanib(1+)

nintedanib(1+) Show first 5 Terms
has_role: angiogenesis inhibitor antineoplastic agent fibroblast growth factor receptor antagonist tyrosine kinase inhibitor vascular endothelial growth factor receptor antagonist

angiogenesis inhibitor antineoplastic agent fibroblast growth factor receptor antagonist tyrosine kinase inhibitor vascular endothelial growth factor receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from nintedanib esylate

Phenotype where environments contain nintedanib esylate

Phenotype modified by environments containing nintedanib esylate

Human Disease / Model Data

Citations