raltegravir

Term ID

CHEBI:82960

Synonyms

MK 0518
MK-0518
MK0518
N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide
raltegravir
raltegravirum

Definition

A pyrimidone that is pyrimidin-4(3H)-one in which the hydrogens at positions 2, 3, 5 and 6 are replaced by 2-[(5-methyl-1,3,4-oxadiazole-2-carbonyl)amino]propan-2-yl, methyl, hydroxy, and N-[(4-fluorophenyl)methyl]aminoacyl groups, respectively. It is an antiretroviral drug used for treatment of HIV infection.

References

cas:518048-05-0
chemspider:16445111
drugbank:DB06817
drugcentral:2352
kegg.drug:D06676
lincs.smallmolecule:LSM-5233
pdb-ccd:RLT
pmc:PMC6809206
pubmed:17133211
pubmed:17428043
pubmed:17569171
pubmed:18095922
pubmed:18174972
pubmed:20118915
pubmed:21030679
pubmed:24097843
pubmed:24145879
pubmed:24277175
pubmed:24397848
pubmed:24872134
pubmed:24962031
pubmed:25017682
pubmed:25114168
pubmed:25162818
pubmed:25162819
pubmed:31525573
pubmed:32448902
pubmed:32661003
pubmed:32675580
pubmed:32728708
pubmed:32925360
pubmed:33099638
pubmed:33136758
pubmed:33163587
pubmed:33369217
pubmed:33493297
pubmed:33527213
pubmed:33667407
pubmed:33670655
pubmed:33779719
pubmed:33831906
pubmed:33993302
reaxys:10696228
wikipedia.en:Raltegravir

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from raltegravir

Phenotype where environments contain raltegravir

Phenotype modified by environments containing raltegravir

Phenotype affecting raltegravir

Human Disease Model