Search Ontology:
ChEBI
MDL-28170
- Term ID
- CHEBI:82818
- Synonyms
-
- benzyl [(2S)-3-methyl-1-oxo-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]amino}butan-2-yl]carbamate
- calpain inhibitor III
- carbobenzoxyvalylphenylalanine aldehyde
- Cbz-Val-Phe-H
- CbzValPheH
- L-benzyloxycarbonyl-L-valyl-L-phenylalaninal
- MDL 28,170
- MDL 28170
- MDL-28170
- MDL28170
- N-benzyloxycarbonyl-L-valyl-L-phenylalaninal
- N-benzyloxycarbonylvalylphenylalaninal
- N-benzyloxycarbonylvalylphenylalanine aldehyde
- N-CBZ-Val-Phe-al
- Z-Val-Phe-al
- Z-Val-Phe-CHO
- Z-Val-Phe-H
- Definition
- A dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor.
- References
-
- CAS:88191-84-8
- LINCS:LSM-2958
- PMID:12001809
- PMID:12820680
- PMID:15275793
- PMID:15282090
- PMID:15777753
- PMID:16817871
- PMID:16842979
- PMID:17600513
- PMID:20657463
- PMID:20874056
- PMID:22077394
- PMID:22253611
- PMID:22356295
- PMID:26087461
- PMID:2849930
- PMID:28663009
- PMID:29039273
- PMID:29728827
- PMID:30528875
- PMID:30876457
- PMID:31198938
- PMID:31618932
- PMID:35202224
- PMID:37090078
- PMID:37484825
- PMID:39326733
- PMID:39591265
- PMID:9302348
- PMID:9637399
- Reaxys:6824325
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
Show first 5 Terms
Show All 6 Terms
Phenotype
Phenotype resulting from MDL-28170
Phenotype where environments contain MDL-28170
Phenotype modified by environments containing MDL-28170
Phenotype affecting MDL-28170
Human Disease Model