angiotensin (1-9)

Term ID

CHEBI:80128

Synonyms

[des-Leu(10)]-angiotensin I
ang-(1-9)
angiotensin I (1-9)
angiotensin-(1-9)
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His
D-R-V-Y-I-H-P-F-H
des-Leu angiotensin I
DRVYIHPFH
L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanyl-L-histidine
L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-L-His

Definition

A nine amino acid peptide which is formed when angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy terminal leucine from angiotensin I. It is a anti-cardiac hypertrophy agent.

References

cas:34273-12-6
kegg.compound:C15851
pubmed:10969042
pubmed:15283675
pubmed:19790042
pubmed:20411619
pubmed:20610862
pubmed:21330937
pubmed:2170511
pubmed:22184331
pubmed:23029101
pubmed:23884911
pubmed:24177599
pubmed:24463937
pubmed:24593683
pubmed:24991795
pubmed:24991796
pubmed:25029123
pubmed:25801006
pubmed:26238180
pubmed:26988149
pubmed:2780412
pubmed:27978950
pubmed:27978951
pubmed:29962859
pubmed:30048754
pubmed:30179588
pubmed:31563322
pubmed:32152556

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from angiotensin (1-9)

Phenotype where environments contain angiotensin (1-9)

Phenotype modified by environments containing angiotensin (1-9)

Phenotype affecting angiotensin (1-9)

Human Disease Model