SB-202190

Term ID

CHEBI:79090

Synonyms

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole
4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
SB 202190
SB202190

Definition

A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) alpha and beta.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: imidazoles organofluorine compound phenols pyridines

imidazoles organofluorine compound phenols pyridines Show first 5 Terms
has_role: apoptosis inducer EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor

apoptosis inducer EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from SB-202190

Phenotype where environments contain SB-202190

Phenotype modified by environments containing SB-202190

Human Disease / Model Data

Citations