Search Ontology:
ChEBI

CK-666

Term ID
CHEBI:78843
Synonyms
  • 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • CK 666
  • CK-0944666
  • CK666
Definition
A member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from CK-666
Phenotype where environments contain CK-666
Phenotype modified by environments containing CK-666
Human Disease / Model Data
Citations
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