oligomycin C

Term ID

CHEBI:7752

Synonyms

• (1R,4E,5'S,6S,6'S,7R,8S,10R,11S,12S,14S,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-
• 12-deoxy-oligomycin A
• 12-deoxyoligomycin A

Definition

An oligomycin with formula C45H74O10 that is oligomycin A in which the hydroxy group that is alpha- to a macrolide keto group has been replaced by a hydrogen. It is an inhibitor of the mitochondrial F1F0 ATP synthase.

References

• CAS:11052-72-5
• KEGG:C11313
• LINCS:LSM-43165
• MetaCyc:CPD-21958
• PDBeChem:EF4
• PMID:11304197
• PMID:25300113
• PMID:25849761
• PMID:26883908
• PMID:34119221

Ontology

ChEBI  ( EBI )

Resources

CTD