oligomycin B

Term ID

CHEBI:7751

Synonyms

• (1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27S,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-5',6'-dihydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2
• 28-oxo-oligomycin A

Definition

An oligomycin with formula C45H72O12 that is oligomycin A in which the spirocyclic ring bearing the 2-hydroxypropyl substituent has been substituted by an oxo group at the carbon which is directly attached to the spirocentre. It is a nonselective inhibitor of the mitochondrial F1F0 ATP synthase.

References

• CAS:11050-94-5
• KEGG:C11312
• MetaCyc:CPD-21957
• PDBeChem:EFB
• PMID:11946434
• PMID:12902194
• PMID:21784985
• PMID:25300113
• PMID:26672111
• PMID:27354061
• PMID:32804955
• PMID:4107834

Ontology

ChEBI  ( EBI )

Resources

CTD