methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Term ID

CHEBI:76917

Synonyms

methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Definition

A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a methoxycarbonyl group at position 3, an o-nitrophenyl group at position 4, and an isobutoxycarbonyl group at position 5. The racemate, a calcium channel blocker, is used in the treatment of hypertension and angina pectoris.

References

CAS:63675-72-9
KEGG:C07699
KEGG:D00618
LINCS:LSM-5172

Ontology

ChEBI ( EBI )

Relationships

is a type of: C-nitro compound dicarboxylic acids and O-substituted derivatives diester dihydropyridine methyl ester

C-nitro compound dicarboxylic acids and O-substituted derivatives diester dihydropyridine methyl ester Show first 5 Terms
has subtype: (R)-nisoldipine (S)-nisoldipine

(R)-nisoldipine (S)-nisoldipine Show first 5 Terms

Phenotype

Phenotype resulting from methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Phenotype where environments contain methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Phenotype modified by environments containing methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Human Disease / Model Data

Citations