Search Ontology:
ChEBI

ibrutinib

Term ID
CHEBI:76612
Synonyms
  • 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one
  • ibrutinib
  • ibrutinibum
  • IMBRUVICA
  • PCI 32765
  • PCI-32765
  • PCI32765
Definition
A member of the class of acrylamides that is (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from ibrutinib
Phenotype where environments contain ibrutinib
Phenotype modified by environments containing ibrutinib
Human Disease / Model Data
Citations
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