Search Ontology:
ChEBI
dolutegravir
- Term ID
- CHEBI:76010
- Synonyms
-
- (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- S/GSK1349572
- Definition
- A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1.
- References
-
- CAS:1051375-16-6
- Drug_Central:4805
- KEGG:D10066
- PDBeChem:DLU
- PMID:22018760
- PMID:22205735
- PMID:22878423
- PMID:22905856
- PMID:23075918
- PMID:23132334
- PMID:23225901
- PMID:23295935
- PMID:23306000
- PMID:23413040
- PMID:23432922
- PMID:23455469
- PMID:23669385
- PMID:23777012
- PMID:23798668
- PMID:23807273
- PMID:23817375
- PMID:23824675
- PMID:23830355
- PMID:23845180
- PMID:23885999
- PMID:23942060
- PMID:24052331
- PMID:24074642
- PMID:24096683
- Patent:EP2602260
- Patent:WO2006116764
- Reaxys:12732602
- Wikipedia:Dolutegravir
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_base_of
-
- is_conjugate_acid_of
-
Show first 5 Terms
Phenotype
Phenotype resulting from dolutegravir
Phenotype where environments contain dolutegravir
Phenotype modified by environments containing dolutegravir
Human Disease / Model Data
Citations