5-chloro-7-iodoquinolin-8-ol

Term ID

CHEBI:74460

Synonyms

• 5-Chlor-7-jod-8-hydroxy-chinolin
• 5-chloro-7-iodo-8-hydroxyquinoline
• 5-chloro-7-iodo-8-quinolinol
• 5-chloro-7-iodoquinolin-8-ol
• 5-chloro-8-hydroxy-7-iodoquinoline
• 7-iodo-5-chloro-8-hydroxyquinoline
• 7-iodo-5-chloroxine
• chloroiodoquin
• clioquinol
• clioquinolum
• iodochlorhydroxyquinoline
• iodochlorohydroxyquin
• iodochloroxyquinoline

Definition

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.

References

• CAS:130-26-7
• DrugBank:DB04815
• Drug_Central:681
• KEGG:D03538
• LINCS:LSM-2186
• PDBeChem:CQL
• PMID:15074181
• PMID:15651505
• PMID:16087879
• PMID:185949
• PMID:20651355
• PMID:21080020
• PMID:21199452
• PMID:21247386
• PMID:21426304
• PMID:21899946
• PMID:22248233
• PMID:22269164
• PMID:22627294
• PMID:226725
• PMID:23044228
• PMID:23360710
• PMID:23627708
• Patent:DE117767
• Patent:US641491
• Reaxys:153637
• Wikipedia:Clioquinol

Ontology

ChEBI  ( EBI )

Resources

CTD