papulacandin A

Term ID

CHEBI:72611

Synonyms

• (1S,3'R,4'R,5'R,6'R)-5'-({6-O-[(2E,4E)-deca-2,4-dienoyl]-beta-D-galactopyranosyl}oxy)-3',5,7-trihydroxy-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[2-benzofuran-1,2'-pyran]-4'-yl (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetrae
• A-32283-A
• papulacandin-A

Definition

A papulacandin substituted by a (2E,4E)-deca-2,4-dienoyl chain at the O-(6') position and a (2E,4E,7S,8E,10E,14S)-7-hydroxy-8,14-dimethylhexadeca-2,4,8,10-tetraenoyl chain at the O-(3) position. It is a carbohydrate-containing antibiotic from the deuteromycetous fungus Papularia sphaerosperma which shows potent antifungal activity against Candida albicans.

References

• CAS:61036-46-2
• PMID:20711516
• PMID:7440418
• Reaxys:6444369

Ontology

ChEBI  ( EBI )