Search Ontology:
ChEBI
bedaquiline
- Term ID
- CHEBI:72292
- Synonyms
-
- (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(1-naphthyl)-1-phenylbutan-2-ol
- 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol
- bedaquilina
- bedaquiline
- bedaquilinum
- R 207910
- R207910
- TMC 207
- TMC-207
- TMC207
- Definition
- A quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria.
- References
-
- CAS:654653-93-7
- CAS:843663-66-1
- Drug_Central:4741
- KEGG:C14122
- KEGG:D09872
- PMID:18948422
- PMID:19954909
- PMID:20038615
- PMID:21659613
- PMID:21858172
- PMID:21877185
- PMID:22126739
- PMID:22155815
- PMID:22279595
- PMID:22332895
- PMID:22354303
- PMID:22391540
- PMID:22470112
- PMID:22615276
- PMID:22622957
- PMID:22762423
- PMID:22828481
- PMID:22926573
- PMID:22991970
- PMID:23089752
- PMID:23291974
- Patent:WO2005117875
- Patent:WO2006067048
- Reaxys:10733008
- Wikipedia:Bedaquiline
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Show All 6 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from bedaquiline
Phenotype where environments contain bedaquiline
Phenotype modified by environments containing bedaquiline
Human Disease / Model Data
Citations