(+-)-chartaceone E

Term ID

CHEBI:68937

Synonyms

• (5E)-7-{6-[(1E)-6-carboxy-1-phenylhex-1-en-3-yl]-5,7-dihydroxy-4-oxo-2-phenyl-3,4-dihydro-2H-chromen-8-yl}-7-phenylhept-5-enoic acid

Definition

A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7, a 6-carboxy-1-phenylhex-2-en-1-yl group at position 8 and 6-carboxy-1-phenylhex-2-en-3-yl groups at position 6. It has been isolated as a racemate from the bark of Cryptocarya chartacea and exhibits inhibitory activity against dengue virus NS5 polymerase.

References

• PMID:22050318
• Reaxys:22123629

Ontology

ChEBI  ( EBI )