18-oxotryprostatin A

Term ID

CHEBI:66842

Synonyms

(3S,8aS)-3-{[6-methoxy-2-(3-methylbut-2-enoyl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Definition

An indole alkaloid that is tryprostatin A substituted by an oxo substituent at position 18. Isolated from Aspergillus sydowii, it exhibits cytotoxicity.

References

PMID:18505285
Reaxys:18842461

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether aromatic ketone dipeptide enone indole alkaloid ... Show All 7 Terms

aromatic ether aromatic ketone dipeptide enone indole alkaloid indoles pyrrolopyrazine Show first 5 Terms
has_functional_parent: brevianamide F

brevianamide F Show first 5 Terms
has_role: antineoplastic agent Aspergillus metabolite

antineoplastic agent Aspergillus metabolite Show first 5 Terms

Phenotype

Phenotype resulting from 18-oxotryprostatin A

Phenotype where environments contain 18-oxotryprostatin A

Phenotype modified by environments containing 18-oxotryprostatin A

Human Disease / Model Data

Citations