xanthohumol B

Term ID

CHEBI:66334

Synonyms

• (2E)-1-(3,5-dihydroxy-7-methoxy-2,2-dimethyl-3,4-dihydro-2H-chromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
• Dehydrocycloxanthohumol hydrate
• rac-(E)-1-(3,5-dihydroxy-7-methoxy-2,2-dimethyl-3,4-dihydrochromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
• rac-6'',6''-dimethyl-5''-hydroxy-4'',5''-dihydropyrano[2'',3'':4',3']-4,2'-dihydroxy-6'-methoxychalcone
• rac-6-[3,4-dihydro-3,5-dihydroxy-7-methoxy-2,2-dimethyl-2H-benzo[b]pyrano]-3-(4-hydroxyphenyl)-2-propen-1-one

Definition

A member of the class of chalcones that is (2E)-1-(3,4-dihydro-2H-chromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one substituted by hydroxy groups at position 3 and 5, a methoxy group at position 7 and geminal methyl groups at position 2. It has been isolated as a racemate from Humulus lupulus and has been shown to exhibit inhibitory activity against nitric oxide production.

References

• HMDB:HMDB0034867
• LIPID_MAPS_instance:LMPK12120299
• MetaCyc:CPD-7127
• PMID:10418944
• PMID:10737704
• PMID:15679315
• PMID:9366096
• Patent:EP2277526
• Patent:US2007218155
• Patent:WO2008095189
• Reaxys:7828262

Ontology

ChEBI  ( EBI )