rotundifolioside J

Term ID

CHEBI:66317

Synonyms

• (3beta,16alpha)-16-hydroxy-13,28-epoxyurs-11-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->2)-6-deoxy-beta-D-galactopyranoside
• 13beta,28-epoxy-16alpha-hydroxyurs-11-en-3beta-yl alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranosyl-(1->2)-beta-D-fucopyranoside

Definition

A triterpenoid saponin that consists of urs-11-ene substituted by an epoxy group across positions 13 and 28, a hydroxy group at position 16 and a α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-β-D-fucopyranosyloxy residue at position 3 (the 3β,16α stereoisomer). Isolated from the fruits of Bupleurum rotundifolium, it exhibits antiproliferative activity against cancer cells.

References

• pubmed:12672986
• reaxys:9468714

Ontology

ChEBI  ( EBI )