topopyrone C

Term ID

CHEBI:66254

Synonyms

5,9,11-trihydroxy-2-methyl-4H-naphtho[2,3-h]chromene-4,7,12-trione

Definition

A naphthochromene that is 4H-naphtho[2,3-h]chromene-4,7,12-trione substituted by hydroxy groups at positions 5, 9 and 11 and a methyl group at position 2. It is isolated from fungal strains Phoma and Penicillium and acts as an inhibitor of the enzyme topoisomerase I.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: naphthochromene p-quinones phenols

naphthochromene p-quinones phenols Show first 5 Terms
has_role: antimicrobial agent antineoplastic agent antiviral agent EC 5.99.1.2 (DNA topoisomerase) inhibitor Penicillium metabolite

antimicrobial agent antineoplastic agent antiviral agent EC 5.99.1.2 (DNA topoisomerase) inhibitor Penicillium metabolite Show first 5 Terms

Phenotype

Phenotype resulting from topopyrone C

Phenotype where environments contain topopyrone C

Phenotype modified by environments containing topopyrone C

Human Disease / Model Data

Citations