topopyrone A

Term ID

CHEBI:66252

Synonyms

10-chloro-5,9,11-trihydroxy-2-methyl-4H-naphtho[2,3-h]chromene-4,7,12-trione

Definition

A naphthochromene that is 4H-naphtho[2,3-h]chromene-4,7,12-trione substituted by a chloro group at position 10, hydroxy groups at positions 5, 9 and 11 and a methyl group at position 2. It is isolated from a fungal strain Phoma sp.BAUA2861 and acts as an inhibitor of the enzyme topoisomerase I.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: naphthochromene organochlorine compound p-quinones phenols

naphthochromene organochlorine compound p-quinones phenols Show first 5 Terms
has_role: antimicrobial agent antineoplastic agent antiviral agent EC 5.99.1.2 (DNA topoisomerase) inhibitor metabolite

antimicrobial agent antineoplastic agent antiviral agent EC 5.99.1.2 (DNA topoisomerase) inhibitor metabolite Show first 5 Terms

Phenotype

Phenotype resulting from topopyrone A

Phenotype where environments contain topopyrone A

Phenotype modified by environments containing topopyrone A

Human Disease / Model Data

Citations