colossolactone V

Term ID

CHEBI:65649

Synonyms

(22R)-3,4-seco-19,22-diacetoxy-4-hydroxylanosta-8,24(Z)-dien-3,26-dioic acid 3-methylester
(2Z,5R,6S)-5-(acetyloxy)-6-[(3R,3aR,6R,7R,9bR)-6-[(acetyloxy)methyl]-7-(2-hydroxypropan-2-yl)-6-(3-methoxy-3-oxopropyl)-3a,9b-dimethyl-2,3,3a,4,5,6,7,8,9,9b-decahydro-1H-cyclopenta[a]naphthalen-3-yl]-2-methylhept-2-enoic acid

Definition

A tricyclic triterpenoid that is 3,4-secolanosta-8,24-diene-3,26-dioic acid 3-methylester substituted by acetoxy groups at positions 19 and 22 and a hydroxy group at position 4. It is isolated from the fruiting bodies of the Vietnamese mushroom Ganoderma colossum and displays inhibitory activity towards the enzyme HIV protease.

References

PMID:18547117
Reaxys:18836351

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate ester dicarboxylic acid monoester methyl ester tertiary alcohol tricyclic triterpenoid

acetate ester dicarboxylic acid monoester methyl ester tertiary alcohol tricyclic triterpenoid Show first 5 Terms
has_parent_hydride: lanostane

lanostane Show first 5 Terms
has_role: fungal metabolite HIV protease inhibitor

fungal metabolite HIV protease inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from colossolactone V

Phenotype where environments contain colossolactone V

Phenotype modified by environments containing colossolactone V

Human Disease / Model Data

Citations