Search Ontology:
ChEBI

AS-186a

Term ID
CHEBI:65443
Synonyms
  • 11-hydroxy-3-[(1S)-1-hydroxy-3-methylbutyl]-4-methoxy-9-methyl-5H,7H-dibenzo[b,g][1,5]dioxocin-5-one
  • penicillide
  • vermixocin A
Definition
A dibenzodioxocine that is 5H,7H-dibenzo[b,g][1,5]dioxocin-5-one substituted by a hydroxy group at position 11, a (1S)-1-hydroxy-3-methylbutyl group at position 3 and a methoxy and a methyl group at positions 4 and 9 respectively. It is isolated from the culture broth of Penicillium asperosporum and acts as an acyl-CoA:cholesterol acyltransferase inhibitor.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from AS-186a
Phenotype where environments contain AS-186a
Phenotype modified by environments containing AS-186a
Human Disease / Model Data
Citations