arisugacin C

Term ID

CHEBI:65437

Synonyms

(4aS,6aR,12aR,12bR)-4a-hydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-tetramethyl-1,4a,5,6,6a,12,12a,12b-octahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,11(4H)-dione

Definition

An organic heterotetracyclic compound that is 4,4,6a,12b-tetramethyl-1,4a,5,6,6a,12,12a,12b-octahydro-2H,11H-benzo[f]pyrano[4,3-b]chromene-3,11(4H)-dione substituted at position 4a by a hydroxy and and at position 9 by 4-methoxyphenyl group (the 4aS,6aR,12aR,12bR stereoisomer). Isolated from the culture broth of Penicillium, it acts as a selective inhibitor of acetylcholinesterase.

References

PMID:10724008
Reaxys:8521391

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether cyclic ketone delta-lactone organic heterotetracyclic compound tertiary alcohol

aromatic ether cyclic ketone delta-lactone organic heterotetracyclic compound tertiary alcohol Show first 5 Terms
has_role: antimicrobial agent EC 3.1.1.7 (acetylcholinesterase) inhibitor Penicillium metabolite

antimicrobial agent EC 3.1.1.7 (acetylcholinesterase) inhibitor Penicillium metabolite Show first 5 Terms

Phenotype

Phenotype resulting from arisugacin C

Phenotype where environments contain arisugacin C

Phenotype modified by environments containing arisugacin C

Human Disease / Model Data

Citations