loratadine

Term ID

CHEBI:6538

Synonyms

• 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
• Aerotina
• Alarin
• Alavert
• Alerpriv
• Allerclear
• Civeran
• Claratyne
• Claritin
• ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
• Loracert
• Loradamed
• Loradex
• Lorastine
• loratadina
• loratadine
• loratadinum
• Loratyne
• Wal-itin

Definition

A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders.

References

• CAS:79794-75-5
• Chemspider:3820
• DrugBank:DB00455
• Drug_Central:1605
• FooDB:FDB023577
• HMDB:HMDB0005000
• KEGG:D00364
• LINCS:LSM-5891
• PMID:15627436
• PMID:24134630
• PMID:31315424
• PMID:31576110
• PMID:32312261
• PMID:32694422
• PMID:32877950
• PMID:33550204
• PMID:33673552
• PMID:33963858
• PMID:34121623
• PMID:34306392
• PMID:7522069
• Reaxys:4273483
• Wikipedia:Loratadine

Ontology

ChEBI  ( EBI )

Resources

CTD