Search Ontology:
ChEBI
vemurafenib
- Term ID
- CHEBI:63637
- Synonyms
-
- N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide
- PLX 4032
- PLX-4032
- PLX4032
- RG 7204
- RG-7204
- RG7204
- Ro 51-85426
- RO 5185426
- RO-51-85426
- RO-5185426
- RO5185426
- vemurafenib
- vemurafenibum
- Zelboraf
- Definition
- A pyrrolopyridine that is 1H-pyrrolo[2,3-b]pyridine which is substituted at position 5 by a p-chlorophenyl group and at positions 3 by a 3-amino-2,6-difluorobenzoyl group, the amino group of which has undergone formal condensation with propane-1-sulfonic acid to give the corresponding sulfonamide. An inhibitor of BRAF and other kinases.
- References
-
- CAS:918504-65-1
- DrugBank:DB08881
- Drug_Central:4185
- KEGG:D09996
- LINCS:LSM-1068
- PDBeChem:032
- PMID:21609436
- PMID:21639808
- PMID:22028422
- PMID:22037033
- PMID:22083257
- PMID:22180495
- PMID:23866896
- PMID:29999925
- PMID:33595357
- PMID:34433660
- PMID:35740068
- PMID:36396045
- PMID:36431901
- PMID:36598578
- PMID:36612138
- PMID:36713531
- PMID:36765875
- PMID:36855200
- PMID:36906728
- PMID:36977328
- PMID:37021539
- PMID:37106808
- PMID:37215493
- PMID:37216396
- PMID:37309702
- PMID:37325052
- PMID:37419396
- PMID:37436162
- PMID:37446932
- PMID:37456058
- PMID:37459870
- PMID:37459873
- Patent:WO2010114928
- Reaxys:12833468
- Wikipedia:Vemurafenib
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from vemurafenib
Phenotype where environments contain vemurafenib
Phenotype modified by environments containing vemurafenib
Human Disease / Model Data
Citations