metamizole

Term ID

CHEBI:62088

Synonyms

(antipyrinylmethylamino)methanesulfonic acid
[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonic acid
[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid
metamizol
metamizolum
N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)-N-methylaminomethanesulfonic acid

Definition

A pyrazole that is antiipyrine substituted at C-4 by a methyl(sulfomethyl)amino group, the sodium salt of which, metamizole sodium, was widely used as a powerful analgesic and antipyretic, but withdrawn from many markets from the 1970s due to a risk of causing risk of causing agranulocytosis.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: amino sulfonic acid pyrazoles

amino sulfonic acid pyrazoles Show first 5 Terms
has_functional_parent: antipyrine

antipyrine Show first 5 Terms
has_role: anti-inflammatory agent antipyretic antirheumatic drug cyclooxygenase 3 inhibitor non-narcotic analgesic ... Show All 7 Terms

anti-inflammatory agent antipyretic antirheumatic drug cyclooxygenase 3 inhibitor non-narcotic analgesic peripheral nervous system drug prodrug Show first 5 Terms
inverse is_conjugate_base_of: metamizole(1-)

metamizole(1-) Show first 5 Terms
is_conjugate_acid_of: metamizole(1-)

metamizole(1-) Show first 5 Terms

Phenotype

Phenotype resulting from metamizole

Phenotype where environments contain metamizole

Phenotype modified by environments containing metamizole

Human Disease / Model Data

Citations