Search Ontology:
ChEBI

afatinib

Term ID
CHEBI:61390
Synonyms
  • (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
  • afatinib
  • afatinibum
  • BIBW 2992
Definition
A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
inverse has_part
Phenotype
Phenotype resulting from afatinib
Phenotype where environments contain afatinib
Phenotype modified by environments containing afatinib
Human Disease / Model Data
Citations
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