formoterol

Term ID

CHEBI:5147

Synonyms

(+-)-2'-hydroxy-5'-((RS)-1-hydroxy-2-(((RS)-p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide
(+-)-formoterol
(R*,R*)-(+-)-N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide
formoterol
formoterolum
N-{2-hydroxy-5-[(1RS)-1-hydroxy-2-{[(2RS)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide
rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide

Definition

A racemate consisting of equal amounts of arformoterol (the active enantiomer) and (S,S)-formoterol (the inactive enantiomer). Its fumaric acid salt is used as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema).

References

CAS:73573-87-2
DrugBank:DB00983
KEGG:C07805
KEGG:D07990
Patent:DE2305092
Patent:US3994974
Reaxys:6741801
Wikipedia:Formoterol

Ontology

ChEBI ( EBI )

Relationships

is a type of: racemate

racemate Show first 5 Terms
has_part: (S,S)-formoterol arformoterol

(S,S)-formoterol arformoterol Show first 5 Terms
has_role: anti-asthmatic drug beta-adrenergic agonist bronchodilator agent

anti-asthmatic drug beta-adrenergic agonist bronchodilator agent Show first 5 Terms
inverse is_conjugate_acid_of: formoterol(1+)

formoterol(1+) Show first 5 Terms
is_conjugate_base_of: formoterol(1+)

formoterol(1+) Show first 5 Terms

Phenotype

Phenotype resulting from formoterol

Phenotype where environments contain formoterol

Phenotype modified by environments containing formoterol

Human Disease / Model Data

Citations