podophyllotoxin

Term ID

CHEBI:50305

Synonyms

• (-)-podophyllotoxin
• (5R,5aR,8aR,9R)-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
• 9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE
• Condylox
• Podofilox
• Podophyllinic acid lactone
• Podophyllotoxin
• Podophyllotoxin 7
• PPT

Definition

An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts.

References

• cas:518-28-5
• drugbank:DB01179
• drugcentral:3481
• hmdb:HMDB0031452
• kegg.compound:C10874
• kegg.drug:D05529
• knapsack:C00000610
• lincs.smallmolecule:LSM-3055
• pdb-ccd:POD
• pubmed:15803102
• pubmed:22621772
• pubmed:23161544
• pubmed:23798883
• pubmed:8112825
• reaxys:99163
• wikipedia.en:Podophyllotoxin

Ontology

ChEBI  ( EBI )

Resources

CTD