E3040

Term ID

CHEBI:4732

Synonyms

5,7-dimethyl-2-(methylamino)-4-(pyridin-3-ylmethyl)-1,3-benzothiazol-6-ol
6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole
E-3040
E3040

Definition

A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by a methylnitrilo group, (pyridin-3-yl)methyl group, methyl group, hydroxy group and methyl group at position 2,4,5,6 and 7, respectively. It is a dual inhibitor of 5-lipoxygenase and thromboxane A2 synthetase and exhibits anti-inflammatory properties. The drug was being developed by Eisai (Tokyo, Japan) for the treatment of bowel disease.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: benzothiazoles organic hydroxy compound pyridines secondary amino compound

benzothiazoles organic hydroxy compound pyridines secondary amino compound Show first 5 Terms
has_role: anti-inflammatory drug EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor uricosuric drug

anti-inflammatory drug EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor uricosuric drug Show first 5 Terms
inverse has_functional_parent: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl hydrogen sulfate E3040 glucuronide

5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl hydrogen sulfate E3040 glucuronide Show first 5 Terms

Phenotype

Phenotype resulting from E3040

Phenotype where environments contain E3040

Phenotype modified by environments containing E3040

Human Disease / Model Data

Citations