dobutamine

Term ID

CHEBI:4670

Synonyms

• (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
• 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
• 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
• 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
• DL-dobutamine
• dobutamina
• dobutamine
• dobutaminum
• rac-dobutamine
• racemic-dobutamine

Definition

A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.

References

• CAS:34368-04-2
• DrugBank:DB00841
• Drug_Central:937
• HMDB:HMDB0014979
• KEGG:C06967
• KEGG:D03879
• LINCS:LSM-1807
• PMID:11280019
• PMID:11950781
• PMID:18323735
• PMID:22537238
• Patent:DE2317710
• Patent:US3987200
• Reaxys:2946389
• Wikipedia:Dobutamine

Ontology

ChEBI  ( EBI )

Resources

CTD