ciclopirox

Term ID

CHEBI:453011

Synonyms

• 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone
• 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
• ciclopirox
• ciclopiroxum

Definition

A cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, respectively. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections.

References

• beilstein:1533423
• cas:29342-05-0
• drugbank:DB01188
• drugcentral:636
• kegg.drug:D03488
• lincs.smallmolecule:LSM-5307
• patent:US3883545
• pubmed:16854048
• pubmed:17253868
• wikipedia.en:Ciclopirox

Ontology

ChEBI  ( EBI )

Resources

CTD